[Microwave-assisted extraction technology of skin-lightning agent in Rhizoma Typhonii].

The microwave-assisted extraction (MAE) technology of skin-lightning agent in Rhizoma Typhonii was studied and the relative inhibitory activity of the extract against tyrosinase was used as evaluating criterion. It was concluded that the optimal condition was two doses of microwave radiation (450 W) for 7 min with a mass ratio of water to material of 10: 1. The dry extract of Rhizoma Typhonii with 20.9% yield and 47.1% relative inhibitory activity against tyrosinase was obtained. Compared with direct-heating extraction, MAE can shorten extracting duration, and improve relative inhibitory activity of the extract against tyrosinase.