Use of surodex in phacotrabeculectomy surgery.
Am J Ophthalmol
; 139(5): 927-8, 2005 May.
Article
en En
| MEDLINE
| ID: mdl-15860309
ABSTRACT
PURPOSE:
To evaluate the use of Surodex (Oculex Pharmaceuticals, Sunnyvale, California) a drug delivery system incorporating 60 micrograms of dexamethasone in a pellet, in phacotrabeculectomy surgery.DESIGN:
Nonrandomized, prospective, interventional case series.METHODS:
Phacotrabeculectomy was performed on 37 Asian subjects with primary open-angle glaucoma (POAG) using a standardized technique. All subjects received a Surodex pellet underneath the scleral flap. Results were compared with those of 31 POAG subjects who had undergone phacotrabeculectomy augmented with 50 mg/ml of intraoperative 5-fluorouracil (5-FU) during the same period.RESULTS:
Mean follow-up in months was 19.7 +/- 7.9 and 22.1 +/- 6.2 for the Surodex and 5-FU groups, respectively (P = .29). There was a 20.1% decrease in intraocular pressure in the Surodex group compared with 28.5% decrease in the 5-FU group (P = .6). Postoperative complications occurred in three cases (8.1%) and six cases (19.3%), respectively (P = .04).CONCLUSIONS:
Combined phacotrabeculectomy surgery augmented by intra-scleral placement of Surodex results in good control of IOP and a low incidence of complications.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Dexametasona
/
Trabeculectomía
/
Glaucoma de Ángulo Abierto
/
Sistemas de Liberación de Medicamentos
/
Facoemulsificación
/
Glucocorticoides
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
Idioma:
En
Revista:
Am J Ophthalmol
Año:
2005
Tipo del documento:
Article