Classic Kaposi's sarcoma in Sardinia: HLA positive and negative associations.
Int J Dermatol
; 44(9): 743-5, 2005 Sep.
Article
en En
| MEDLINE
| ID: mdl-16135142
ABSTRACT
BACKGROUND:
The incidence of classic Kaposi's sarcoma (CKS) in northern Sardinia is one of the highest in the world.METHODS:
Sixty-two patients with CKS were typed for class I and class II antigens. All patients had been born and were living in northern Sardinia.RESULTS:
In the Sardinian patients, we observed a positive CKS association with Cw7, DRB1*1104, DRB1*1302, DQA1*0302, and DQB1*0604, and a negative CKS association with A30, B58, Cw5, DRB1*1601, and DQB1*0502.CONCLUSIONS:
The strong positive CKS association with DRB1*1104 and DQB1*0604 and negative association with B58 are particularly significant and further support the notion of a genetic predisposition to CKS.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sarcoma de Kaposi
Tipo de estudio:
Etiology_studies
/
Incidence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Int J Dermatol
Año:
2005
Tipo del documento:
Article
País de afiliación:
Italia