The Young's modulus of fetal preterm and term amniotic membranes.
Eur J Obstet Gynecol Reprod Biol
; 128(1-2): 103-7, 2006.
Article
en En
| MEDLINE
| ID: mdl-16442204
ABSTRACT
OBJECTIVE:
To examine the Young's modulus of the human amniotic membranes, as well as its relationship to gestational age. To determine whether cellular and material-related parameters affect this modulus. STUDYDESIGN:
In a prospective study at the Obstetric outpatient clinic of the University Hospital Zurich Young's modulus, thickness and mesenchymalepithelial cell ratio of amniotic membranes of preterm (N=23) and term (N=40) placentae were examined. Significance (P<0.05) was calculated with the Mann-Whitney two-sample rank sum test and Wilcoxon signed rank test, while correlations were made using the Spearman's correlation.RESULTS:
The Young's modulus of preterm amniotic membranes was significantly higher than that of term membranes. It varied within the same amniotic membrane. The thickness of the amnion in both preterm and term membranes did not differ significantly. The thinner the preterm and term amniotic membranes, the higher the Young's modulus was. There was no relation to the mesenchymalepithelial cell ratio in the amnion.CONCLUSIONS:
Preterm amniotic membranes are stiffer than term amniotic membranes. Tentatively, we hypothesise that there may be a correlation between the extracellular matrix components and the elastic properties of the membrane.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Rotura Prematura de Membranas Fetales
/
Edad Gestacional
/
Amnios
/
Modelos Teóricos
Tipo de estudio:
Observational_studies
/
Prognostic_studies
Límite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Eur J Obstet Gynecol Reprod Biol
Año:
2006
Tipo del documento:
Article
País de afiliación:
Suiza