Feasibility of a type 1 diabetes primary prevention trial using 2000 IU vitamin D3 in infants from the general population with increased HLA-associated risk.
Ann N Y Acad Sci
; 1079: 310-2, 2006 Oct.
Article
en En
| MEDLINE
| ID: mdl-17130571
ABSTRACT
Recent epidemiologic, immunologic, and NOD mouse studies suggest that intervention in the vitamin D system may be a successful method to prevent type 1 diabetes. Newborns at increased HLA-associated risk are randomized to receive either 400 or 2000 IU vitamin D3 by 1 month of age. We show that recruitment of babies from the general population for identification of HLA-associated risk status followed by enrollment to a randomized controlled prevention trial is feasible in Canada.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Colecalciferol
/
Diabetes Mellitus Tipo 1
/
Antígenos HLA
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Humans
/
Newborn
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Ann N Y Acad Sci
Año:
2006
Tipo del documento:
Article