MPL W515 and JAK2 V617 mutation analysis in patients with refractory anemia with ringed sideroblasts and an elevated platelet count.
Haematologica
; 91(12 Suppl): ECR57, 2006 Dec.
Article
en En
| MEDLINE
| ID: mdl-17194663
ABSTRACT
Discovery of a constitutively activating point mutation of the Janus kinase 2 (JAK2) receptor-associated tyrosine kinase in patients with polycythemia vera (PV) and other BCR/ABL-negative myeloproliferative disorders prompted many groups around the world to examine diverse subsets of patients with myeloid diseases for the prevalence of the JAK2 V617F mutation and its clinical and pathological associations.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Anemia Refractaria
/
Mutación Puntual
/
Mutación Missense
/
Janus Quinasa 2
/
Receptores de Trombopoyetina
/
Anemia Sideroblástica
Tipo de estudio:
Risk_factors_studies
Límite:
Aged80
/
Animals
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Haematologica
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos