Early destructive lesions in the developing brain: clinical and electrographic correlates.
Arq Neuropsiquiatr
; 65(2B): 416-22, 2007 Jun.
Article
en En
| MEDLINE
| ID: mdl-17665007
ABSTRACT
OBJECTIVE:
Early brain insults can cause cavitary lesions including porencephaly (POR) and multicystic encephalopathy (MCE). The objective of this study was to investigate clinical and electrographic correlates associated to these types of destructive brain lesions.METHOD:
Patients with POR and MCE were selected and submitted to clinical and Video-EEG monitoring. The following variables were analyzed demographic data, type of lesion, presence of gliosis, perinatal complications, epilepsy, brain atrophy, and presence and frequency of epileptiform discharges.RESULTS:
Twenty patients were included, 65% males, 35% females, ages ranging from 1 to 40 years, 14 with MCE and 6 with POR. Eighteen patients had hemiparesis, 19 had epilepsy (current or in the past), seven of them had refractory seizures, and 16 had epileptiform discharges. All patients with MCE had gliosis while only 2 with POR had it.CONCLUSIONS:
No correlation was observed between type of lesion and clinical and electrographical outcome. However, a positive correlation was observed between frequency of discharges and presence of brain atrophy, and between MCE and gliosis.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Corteza Cerebral
/
Quistes del Sistema Nervioso Central
/
Encefalomalacia
Tipo de estudio:
Etiology_studies
Límite:
Adolescent
/
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
Idioma:
En
Revista:
Arq Neuropsiquiatr
Año:
2007
Tipo del documento:
Article
País de afiliación:
Brasil