Mortality in patients with left ventricular ejection fraction =30% after primary percutaneous coronary intervention for ST-elevation myocardial infarction.
Am J Cardiol
; 100(5): 793-7, 2007 Sep 01.
Article
en En
| MEDLINE
| ID: mdl-17719322
ABSTRACT
Decreased left ventricular (LV) function is a strong predictor of mortality. Although current guidelines recommend prophylactic implantable cardioverter-defibrillator (ICD) implantation after ST-elevation myocardial infarction and a depressed LV ejection fraction for 1 month, the prognoses of these patients may be better than those observed in randomized trials of ICDs (1-year mortality 6.8% to 19%), particularly because reperfusion treatment has improved, and the use of life-saving drugs is higher. To assess 1-year mortality in patients with depressed LV ejection fractions after primary percutaneous coronary intervention, a prospective, observational study was performed. Data from all patients who survived >/=30 days after primary percutaneous coronary intervention and had LV ejection fractions =30% from 1994 to 2004 were recorded. Of 2,544 patients, 342 (13%) had LV ejection fractions =30%. One-year mortality was 5.8%. Sudden death was the most common cause of death (40%). Patients who died more often had multivessel disease and a higher incidence of recurrent myocardial infarction within 1 year. In conclusion, current mortality in patients with depressed LV ejection fractions after primary percutaneous coronary intervention is much better than that observed in previous ICD trials, and the benefits of ICD therapy in these patients should be further evaluated.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Gasto Cardíaco Bajo
/
Angioplastia Coronaria con Balón
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Disfunción Ventricular Izquierda
/
Electrocardiografía
/
Infarto del Miocardio
Tipo de estudio:
Clinical_trials
/
Guideline
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Am J Cardiol
Año:
2007
Tipo del documento:
Article
País de afiliación:
Países Bajos