New insights into the function of IAP proteins: modulation of the MYC/MAX/MAD network.
Dev Cell
; 14(1): 3-4, 2008 Jan.
Article
en En
| MEDLINE
| ID: mdl-18194645
A growing number of studies have revealed that the inhibitor of apoptosis (IAP) proteins play a variety of cellular roles in addition to suppression of apoptosis. A recent study in Molecular Cell demonstrates that one IAP member, c-IAP1, functions to potentiate the activity of Myc by triggering the ubiquitination and proteasomal degradation of the Myc inhibitory protein Mad1.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Represoras
/
Genes myc
/
Apoptosis
/
Proteínas Inhibidoras de la Apoptosis
/
Factores de Transcripción Básicos con Cremalleras de Leucinas y Motivos Hélice-Asa-Hélice
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Dev Cell
Asunto de la revista:
EMBRIOLOGIA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos