Actin and microtubules: working together to control spindle polarity.
Cancer Cell
; 14(3): 197-9, 2008 Sep 09.
Article
en En
| MEDLINE
| ID: mdl-18772109
ABSTRACT
Centrosomes are frequently amplified in cancer cells, but centrosome clustering pathways act to minimize their detrimental impact on mitosis. Recent data published online in Genes & Developments by Kwon et al. (2008) suggest that these pathways involve microtubule motors, actin, and focal adhesions. Since centrosomal amplification is rarely seen in normal cells, could blocking clustering lead to the selective killing of tumor cells?
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Actinas
/
Centrosoma
/
Microtúbulos
/
Huso Acromático
Límite:
Animals
Idioma:
En
Revista:
Cancer Cell
Asunto de la revista:
NEOPLASIAS
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos