[Ultrasound guided transbronchial needle aspiration as a diagnostic tool for lung cancer and sarcoidosis]. / Przezoskrzelowa biopsja wezlów chlonnych sródpiersia i wnek pluca pod kontrola ultrasonografii wewnatrzoskrzelowej w czasie rzeczywistym w diagnostyce raka pluca i sarkoidozy.
Pneumonol Alergol Pol
; 76(4): 229-36, 2008.
Article
en Pl
| MEDLINE
| ID: mdl-18785127
ABSTRACT
INTRODUCTION:
The aim of the study was to assess the diagnostic yield of ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in mediastinal or hilar adenopathy in 1) staging of non-small cell lung cancer (NSCLC) (97); 2) other malignant neoplasms including small cell lung cancer (SCLC), metastatic neoplasms and Hodgkin's disease (16); 3) NSCLC recurrence (7); 4) sarcoidosis and other non-malignant diseases (29). MATERIAL ANDMETHODS:
Real time EBUS-TBNA was performed under local anaesthesia and sedation in 149 consecutive patients - 237 biopsies in groups of lymph nodes subcarinal (7) - 107, all paratracheal (2R, 2L, 4R, 4L) - 86, hilar (10R, 10L) - 41 and interlobar (11R, 11L) - 3. A mean axis of punctured node was 15 mm (range 7-42 mm). All negative results were verified by transcervical extended bilateral mediastinal lymphadenectomy (TEMLA), mediastinoscopy or thoracotomy.RESULTS:
Lymph node biopsy was technically successful in 92% and was diagnostic in 55% of lung cancer patients and in 85.7% of sarcoidosis patients. In NSCLC staging sensitivity of EBUS-TBNA was 88.7%, specificity 100%, accuracy 92.8% and NPV 83.3% (89.7%, 100%, 94.9% and 90.9% per biopsy), and in the whole group it was 91.5%, 98.7%, 94.6% and 87.3% respectively. In 7.2% of NSCLC staging patients with false negative results of EBUS-TBNA (mainly subcarinal) there was observed partial involvement of metastatic lymph nodes, mean 34.3% (range 10-50%), confirmed by TEMLA.CONCLUSION:
The diagnostic value of EBUS-TBNA is very high in lung cancer, NSCLC staging and sarcoidosis.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sarcoidosis Pulmonar
/
Biopsia con Aguja Fina
/
Neoplasias Pulmonares
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
Pl
Revista:
Pneumonol Alergol Pol
Asunto de la revista:
ALERGIA E IMUNOLOGIA
Año:
2008
Tipo del documento:
Article