Cutaneous bioengineering instrumentation standardization: the Tissue Viability Imager.
Skin Res Technol
; 15(1): 6-13, 2009 Feb.
Article
en En
| MEDLINE
| ID: mdl-19152572
ABSTRACT
BACKGROUND:
Tissue Viability Imaging (TiVi) is a new bioengineering technology intended for remote two-dimensional mapping of skin red blood cell concentration (RBC(conc)). Before use in the laboratory, work-site and dermatology clinic, critical performance parameters of this emerging technology require careful evaluation.OBJECTIVE:
To assess short- and long-term stability, image uniformity, distance and image size dependence, ambient light and curvature influence in a production batch of Tissue Viability Imagers.METHODS:
Four Tissue Viability Imagers from the same production batch were evaluated at two laboratories (one industrial and one dermatological) with respect to critical parameter performance.RESULTS:
The average systematic drift in sensitivity over time was 0.27% and <1.02% for all four units tested. Difference in sensitivity between units was limited to 4.1% and was due to offset rather than gain deviation. Spatial variation in image uniformity was below 3.08% and 1.93% in the corners and centre of an individual image, respectively. This spatial variation could be further reduced to 0.25% and 0.13%, respectively by image normalization. Ambient light from a 40 W bulb or a 11 W fluorescent light source at a distance of 50-60 cm above the object, reduced the recorded values by about 10%, while the camera to object distance and image size had no detectable influence on sensitivity. Curved objects, such as human forearm, demonstrated an edge effect limited to below 10%.CONCLUSION:
The critical TiVi performance parameters evaluated proved stable in relation to expected variations in skin RBC(conc) over time. Calibration by way of a two-point method may reduce differences in sensitivity between instruments to further facilitate inter-laboratory comparison of results.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Piel
/
Fenómenos Fisiológicos de la Piel
/
Análisis Espectral
/
Supervivencia Tisular
/
Interpretación de Imagen Asistida por Computador
/
Dermoscopía
/
Recuento de Eritrocitos
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
Límite:
Humans
País/Región como asunto:
Europa
Idioma:
En
Revista:
Skin Res Technol
Asunto de la revista:
DERMATOLOGIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Suecia