ABC transporters as potential targets for modulation of drug resistance.
Mini Rev Med Chem
; 9(9): 1102-12, 2009 Aug.
Article
en En
| MEDLINE
| ID: mdl-19689406
ABSTRACT
ATP binding cassette transporters are implicated in multidrug resistant phenotypes of tumor cells and may be cancer stem cell markers. Inhibitors of drug efflux pumps represent an emerging group of potentially useful agents for the improvement of antitumor therapy. Here we provide an overview of drug transporter functions and modulation.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Transportadoras de Casetes de Unión a ATP
/
Resistencia a Antineoplásicos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Mini Rev Med Chem
Asunto de la revista:
QUIMICA
Año:
2009
Tipo del documento:
Article
País de afiliación:
Italia