Effects of multiple doses of clarithromycin on the pharmacokinetics of laropiprant in healthy subjects.

Wang, Ying-Hong; Schwartz, Jules I; Luo, Wen-Lin; Jumes, Patricia; Desai, Rajesh; Wenning, Larissa A; Wagner, John A; Lai, Eseng

Wang, Ying-Hong; Schwartz, Jules I; Luo, Wen-Lin; Jumes, Patricia; Desai, Rajesh; Wenning, Larissa A; Wagner, John A; Lai, Eseng.

Afiliación

Wang YH; Department of Drug Metabolism and Pharmacokinetics, Merck Research Laboratories, West Point, PA, USA Retired employee of Merck & Co., Inc., Rahway, NJ, USA Department of Biostatistics, Merck Research Laboratories, Rahway, NJ, USA Department of Clinical Pharmacology, Merck Research Laboratories, Boston, MA, USA Department of Clinical Pharmacokinetics and Pharmacodynamics, Merck Research Laboratories, West Point, PA, USA Department of Clinical Pharmacology, Merck Research Laboratories, Ra

Cardiovasc Ther ; 29(2): 140-5, 2011 Apr.

Article en En | MEDLINE | ID: mdl-20337634

Asunto(s)

Antibacterianos/farmacología; Claritromicina/farmacología; Indoles/farmacocinética; Receptores Inmunológicos/antagonistas & inhibidores; Receptores de Prostaglandina/antagonistas & inhibidores; Adulto; Claritromicina/efectos adversos; Estudios Cruzados; Inhibidores del Citocromo P-450 CYP3A/farmacología; Interacciones Farmacológicas; Femenino; Humanos; Masculino; Persona de Mediana Edad

Palabras clave

Clarithromycin; Drug interactions; Laropiprant; Pharmacokinetics

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Receptores de Prostaglandina / Receptores Inmunológicos / Claritromicina / Indoles / Antibacterianos Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Cardiovasc Ther Asunto de la revista: ANGIOLOGIA / CARDIOLOGIA / TERAPEUTICA Año: 2011 Tipo del documento: Article

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