Ontogenomic study of the relationship between number of gene splice variants and GO categorization.
Bioinformatics
; 26(16): 1945-9, 2010 Aug 15.
Article
en En
| MEDLINE
| ID: mdl-20616384
ABSTRACT
MOTIVATION Splice variation plays important roles in evolution and cancer. Different splice variants of a gene may be characteristic of particular cellular processes, subcellular locations or organs. Although several genomic projects have identified splice variants, there have been no large-scale computational studies of the relationship between number of splice variants and biological function. The Gene Ontology (GO) and tools for leveraging GO, such as GoMiner, now make such a study feasible. RESULTS:
We partitioned genes into two groups those with numbers of splice variantsAVAILABILITY:
Supplementary tables and figures are available at URL http//discover.nci.nih.gov/OG/supplementaryMaterials.html. The Safari browser appears to perform better than Firefox for these particular items.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Empalme Alternativo
/
Genómica
Tipo de estudio:
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2010
Tipo del documento:
Article
País de afiliación:
Estados Unidos