MRI and DWI: feasibility of DWI and ADC maps in the evaluation of placental changes during gestation.
Prenat Diagn
; 30(12-13): 1178-84, 2010 Dec.
Article
en En
| MEDLINE
| ID: mdl-21064115
ABSTRACT
OBJECTIVE:
To establish if a correlation exists between apparent diffusion coefficient (ADC) values, obtained by diffusion-weighted imaging (DWI), and placental aging.METHOD:
The study is divided into a retrospective phase and a prospective one.In the first phase, 145 pregnant women underwent fetal magnetic resonance imaging (MRI) for suspected disorders in several organs. We performed DWI (b value 0, 200 and 700 s/mm(2)) in all the fetuses, evaluating the patients in whom the whole placenta was visible.In the prospective phase, 50 women (52 fetuses) underwent MRI. We performed, in the same patient, two echo-planar sequences with b values of 0, 200 and 700, and 50, 200 and 700 s/mm(2), including the whole placenta.The ADC maps were calculated for all fetuses, divided into three groups based on gestational age (GA) group I 20-26 weeks' gestation, II 27-33, III 34-40.RESULTS:
In the retrospective phase, ADC values had a range from 1 to 2.4 mm(2)/s, showing a significant correlation between ADC values and GA.ADC values obtained by DWI with b value 0, 200 and 700 s/mm(2) had a range from 0.8 to 2.5 mm(2)/s, with an inverse correlation between ADC values and GA, whereas the ADC values with b value 50, 200 and 700 s/mm(2) did not show any statistical correlation (range 1.5-1.7 mm(2)/s).CONCLUSION:
DWI with ADC maps can not be considered markers for placental aging because they are affected by perfusional and circulatory motion.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Placenta
/
Imagen por Resonancia Magnética
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Edad Gestacional
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Imagen de Difusión por Resonancia Magnética
Tipo de estudio:
Diagnostic_studies
/
Evaluation_studies
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Observational_studies
/
Prognostic_studies
Límite:
Adolescent
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Adult
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Female
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Humans
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Pregnancy
Idioma:
En
Revista:
Prenat Diagn
Año:
2010
Tipo del documento:
Article
País de afiliación:
Italia