Sinonasal adenocarcinoma: a rare second malignancy in long term retinoblastoma survivors.
Pediatr Blood Cancer
; 57(4): 693-5, 2011 Oct.
Article
en En
| MEDLINE
| ID: mdl-21548012
ABSTRACT
Retinoblastoma is the most common primary cancer of the eye in children. The incidence of second tumors in survivors of bilateral retinoblastoma and in survivors of unilateral retinoblastoma who presumably carry a germline RB1 mutation is documented. This article describes the previously unrecognized association of sinonasal adenocarcinoma as a second malignancy in retinoblastoma survivors. We present three cases who received radiation therapy as a part of their treatment and developed sinonasal adenocarcinoma as a second malignancy. Sinonasal adenocarcinoma should be considered as a second malignancy in retinoblastoma survivors who present with vague sinus symptoms.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Retinoblastoma
/
Neoplasias de los Senos Paranasales
/
Adenocarcinoma
/
Neoplasias Nasales
/
Neoplasias Primarias Secundarias
/
Neoplasias Inducidas por Radiación
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Aged
/
Humans
/
Male
/
Middle aged
/
Newborn
Idioma:
En
Revista:
Pediatr Blood Cancer
Asunto de la revista:
HEMATOLOGIA
/
NEOPLASIAS
/
PEDIATRIA
Año:
2011
Tipo del documento:
Article
País de afiliación:
Estados Unidos