[Specific expression of microRNA in different tissues of nervous system and expression changes in nerve regeneration].

ABSTRACT

MicroRNA is a class of endogenous non-coding RNA, which regulates the expression of target genes at the post-transcriptional level. In recent years, researches have shown that microRNA expresses specifically and plays an important role in the nervous system under physiological condition. Furthermore, the distribution and expression level of microRNA were changed after the injury of nervous system, which presents important effect on nerve regeneration. This effect of microRNA is significant to the clinical diagnosis and treatment on the injury of nervous system.