Laparoscopic vs. open cholecystectomy for cirrhotic patients: a systematic review and meta-analysis.
Hepatogastroenterology
; 59(118): 1727-34, 2012 Sep.
Article
en En
| MEDLINE
| ID: mdl-22193435
ABSTRACT
BACKGROUND/AIMS:
To compare the safety and effectiveness of laparoscopic cholecystectomy (LC) versus open cholecystectomy (OC) for cirrhotic patients.METHODOLOGY:
The Cochrane Library, MEDLINE, Science Citation Index Expanded, EMBASE and CBM (Chinese Biomedical Database) were searched until August 2011 to indentify relevant and eligible studies.RESULTS:
Twenty three articles with 1316 cirrhotic patients were included. All patients were allocated to the LC group (n=694) or the OC group (n=622). They were primarily in Child-Pugh class A (n=957, 72.7%) and class B (n=343, 26.1%). Meta-analysis of 5 randomized controlled trials (n=284) indicated LC group was associated with the following advantages significant lower surgery-related morbidity, less postoperative complications (e.g. incision hernia, wound infection), shorter hospital stay and less loss of blood. There were no significant differences in the intra-hospital mortality and total operative time between the two groups. Meta-analysis of 19 non-randomized studies (n=1082) showed similar results in favour of LC group. In addition, it showed significant lower intra-hospital mortality and less total operative time in the LC group than the OC group.CONCLUSIONS:
LC is safe and offers various significant benefits over OC. Thus, it should be recommended for compensated cirrhotic patients.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Colecistectomía
/
Colecistectomía Laparoscópica
/
Cirrosis Hepática
Tipo de estudio:
Clinical_trials
/
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
/
Systematic_reviews
Límite:
Humans
Idioma:
En
Revista:
Hepatogastroenterology
Año:
2012
Tipo del documento:
Article
País de afiliación:
China