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Use of skeletal muscle MRI in diagnosis and monitoring disease progression in Duchenne muscular dystrophy.
Finanger, Erika L; Russman, Barry; Forbes, Sean C; Rooney, William D; Walter, Glenn A; Vandenborne, Krista.
Afiliación
  • Finanger EL; Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA. hedderic@ohsu.edu
Phys Med Rehabil Clin N Am ; 23(1): 1-10, ix, 2012 Feb.
Article en En | MEDLINE | ID: mdl-22239869
Studies have shown promise in using various approaches of magnetic resonance imaging (MRI) and magnetic resonance spectroscopy to evaluate skeletal muscle involvement in Duchenne muscular dystrophy. However, these studies have mainly been performed using a cross-sectional design, and the correlation of these MRI changes with disease progression and disease severity has not been fully elucidated. Overall, skeletal muscle MRI is a powerful and sensitive technique in the evaluation of muscle disease, and its use as a biomarker for disease progression or therapeutic response in clinical trials deserves further study.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Músculo Esquelético / Distrofia Muscular de Duchenne Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Phys Med Rehabil Clin N Am Asunto de la revista: MEDICINA FISICA / REABILITACAO Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Imagen por Resonancia Magnética / Músculo Esquelético / Distrofia Muscular de Duchenne Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Phys Med Rehabil Clin N Am Asunto de la revista: MEDICINA FISICA / REABILITACAO Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos