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Activation of sterol-response element-binding proteins (SREBP) in alveolar type II cells enhances lipogenesis causing pulmonary lipotoxicity.
Plantier, Laurent; Besnard, Valérie; Xu, Yan; Ikegami, Machiko; Wert, Susan E; Hunt, Alan N; Postle, Anthony D; Whitsett, Jeffrey A.
Afiliación
  • Plantier L; Section of Neonatology, Perinatal and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 and.
  • Besnard V; Section of Neonatology, Perinatal and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 and.
  • Xu Y; Section of Neonatology, Perinatal and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 and.
  • Ikegami M; Section of Neonatology, Perinatal and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 and.
  • Wert SE; Section of Neonatology, Perinatal and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 and.
  • Hunt AN; Division of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.
  • Postle AD; Division of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, United Kingdom.
  • Whitsett JA; Section of Neonatology, Perinatal and Pulmonary Biology, Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 and. Electronic address: jeff.whitsett@cchmc.org.
J Biol Chem ; 287(13): 10099-10114, 2012 Mar 23.
Article en En | MEDLINE | ID: mdl-22267724
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neumonía / Alveolos Pulmonares / Proteínas de Unión a los Elementos Reguladores de Esteroles / Lipogénesis / Proteínas de la Membrana Límite: Animals Idioma: En Revista: J Biol Chem Año: 2012 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neumonía / Alveolos Pulmonares / Proteínas de Unión a los Elementos Reguladores de Esteroles / Lipogénesis / Proteínas de la Membrana Límite: Animals Idioma: En Revista: J Biol Chem Año: 2012 Tipo del documento: Article