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Reactive oxygen species and mitochondrial sensitivity to oxidative stress determine induction of cancer cell death by p21.
Masgras, Ionica; Carrera, Samantha; de Verdier, Petra J; Brennan, Paul; Majid, Aneela; Makhtar, Wan; Tulchinsky, Eugene; Jones, George D D; Roninson, Igor B; Macip, Salvador.
Afiliación
  • Masgras I; Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Carrera S; Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • de Verdier PJ; Department of Molecular Medicine and Surgery, Urology Laboratory, Karolinska Institutet, 171 76 Stockholm, Sweden.
  • Brennan P; Department of Infection, Immunity, and Biochemistry, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom, and.
  • Majid A; Medical Research Council (MRC) Toxicology Unit, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Makhtar W; Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Tulchinsky E; Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Jones GDD; Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester LE1 9HN, United Kingdom.
  • Roninson IB; Translational Cancer Therapeutics Program Department of Pharmaceutical and Biomedical Sciences, South Carolina College of Pharmacy, University of South Carolina, Columbia, South Carolina 29208.
  • Macip S; Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom. Electronic address: sm460@le.ac.uk.
J Biol Chem ; 287(13): 9845-9854, 2012 Mar 23.
Article en En | MEDLINE | ID: mdl-22311974
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sarcoma / Regulación Neoplásica de la Expresión Génica / Especies Reactivas de Oxígeno / Estrés Oxidativo / Inhibidor p21 de las Quinasas Dependientes de la Ciclina / Mitocondrias Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2012 Tipo del documento: Article País de afiliación: Reino Unido
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sarcoma / Regulación Neoplásica de la Expresión Génica / Especies Reactivas de Oxígeno / Estrés Oxidativo / Inhibidor p21 de las Quinasas Dependientes de la Ciclina / Mitocondrias Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: J Biol Chem Año: 2012 Tipo del documento: Article País de afiliación: Reino Unido