Decreased survival among lung cancer patients with co-morbid tuberculosis and diabetes.
BMC Cancer
; 12: 174, 2012 May 11.
Article
en En
| MEDLINE
| ID: mdl-22578056
ABSTRACT
BACKGROUND:
Comorbid conditions influence the survival of cancer patients. This study evaluated the influence of comorbidity on survival among lung cancer patients.METHODS:
The authors evaluated the medical records of 1111 lung cancer patients of a medical center in Taiwan. Days of survival were calculated for each patient and mortality hazard ratios were estimated for associations with demographic status, comorbidity and cancer stage at diagnosis.RESULTS:
On average, the survival time was slightly longer among women than among men (838±689 vs. 749±654 days, p = 0.050). Survival days increased with age (from 580±526 [≤ 50 years] to 803±693 [≥ 71 years] days, p = 0.020) and decreased with stage (from 1224±656 [stage I] to 489±536 [stage IV] days, p < 0.001). Younger patients were more likely to be diagnosed with lung cancer at a late stage. Compared with lung cancer patients without tuberculosis, those with tuberculosis had a significantly shorter average survival duration (584 vs. 791 days, p = 0.002) and a higher mortality hazard ratio (1.30, 95% CI 1.03 - 1.65). A similar trend was observed in lung cancer patients with diabetes.CONCLUSIONS:
Lung cancer patients with comorbid tuberculosis or diabetes are at an elevated risk of mortality. These patients deserve greater attention while undergoing cancer treatment.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Pulmonares
Límite:
Adult
/
Aged
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Aged80
/
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
BMC Cancer
Asunto de la revista:
NEOPLASIAS
Año:
2012
Tipo del documento:
Article
País de afiliación:
Taiwán