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A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing.
Davies, G; Harris, S E; Reynolds, C A; Payton, A; Knight, H M; Liewald, D C; Lopez, L M; Luciano, M; Gow, A J; Corley, J; Henderson, R; Murray, C; Pattie, A; Fox, H C; Redmond, P; Lutz, M W; Chiba-Falek, O; Linnertz, C; Saith, S; Haggarty, P; McNeill, G; Ke, X; Ollier, W; Horan, M; Roses, A D; Ponting, C P; Porteous, D J; Tenesa, A; Pickles, A; Starr, J M; Whalley, L J; Pedersen, N L; Pendleton, N; Visscher, P M; Deary, I J.
Afiliación
  • Davies G; Department of Psychology, The University of Edinburgh, Edinburgh, UK.
  • Harris SE; 1] Medical Genetics Section, The University of Edinburgh Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, Western General Hospital Edinburgh, Edinburgh, UK [2] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
  • Reynolds CA; Department of Psychology, University of California, Riverside, Riverside, CA, USA.
  • Payton A; Centre for Integrated Genomic Medical Research, University of Manchester, Manchester, UK.
  • Knight HM; CGAT, MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
  • Liewald DC; 1] Department of Psychology, The University of Edinburgh, Edinburgh, UK [2] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
  • Lopez LM; 1] Department of Psychology, The University of Edinburgh, Edinburgh, UK [2] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
  • Luciano M; 1] Department of Psychology, The University of Edinburgh, Edinburgh, UK [2] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
  • Gow AJ; 1] Department of Psychology, The University of Edinburgh, Edinburgh, UK [2] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
  • Corley J; Department of Psychology, The University of Edinburgh, Edinburgh, UK.
  • Henderson R; Department of Psychology, The University of Edinburgh, Edinburgh, UK.
  • Murray C; Department of Psychology, The University of Edinburgh, Edinburgh, UK.
  • Pattie A; Department of Psychology, The University of Edinburgh, Edinburgh, UK.
  • Fox HC; Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
  • Redmond P; Department of Psychology, The University of Edinburgh, Edinburgh, UK.
  • Lutz MW; 1] Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC, USA [2] Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Duke University, Durham, NC, USA.
  • Chiba-Falek O; 1] Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC, USA [2] Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Duke University, Durham, NC, USA.
  • Linnertz C; Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
  • Saith S; Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC, USA.
  • Haggarty P; Nutrition and Epigenetics Group, Rowett Institute of Nutrition and Health, University of Aberdeen, Aberdeen, UK.
  • McNeill G; Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
  • Ke X; Institute of Child Health, University College London, London, UK.
  • Ollier W; Centre for Integrated Genomic Medical Research, University of Manchester, Manchester, UK.
  • Horan M; School of Community-Based Medicine, Neurodegeneration Research Group, University of Manchester, Clinical sciences Building, Salford Royal NHS Foundation Trust, Salford, UK.
  • Roses AD; 1] Division of Neurology, Department of Medicine, Duke University Medical Center, Durham, NC, USA [2] Joseph and Kathleen Bryan Alzheimer's Disease Research Center, Duke University, Durham, NC, USA [3] Zinfandel Pharmaceuticals, Chapel Hill, NC, USA.
  • Ponting CP; CGAT, MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
  • Porteous DJ; 1] Medical Genetics Section, The University of Edinburgh Molecular Medicine Centre, Institute of Genetics and Molecular Medicine, Western General Hospital Edinburgh, Edinburgh, UK [2] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
  • Tenesa A; 1] MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh, UK [2] The Roslin Institute, Royal (Dick) School of Veterinary Studies, The University of Edinburgh, Edinburgh, UK.
  • Pickles A; Clinical Trials Unit, Institute of Psychiatry, London, UK.
  • Starr JM; 1] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK [2] Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, UK.
  • Whalley LJ; Institute of Applied Health Sciences, University of Aberdeen, Aberdeen, UK.
  • Pedersen NL; 1] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden [2] Department of Psychology, University of Southern California, Los Angeles, CA, USA.
  • Pendleton N; School of Community-Based Medicine, Neurodegeneration Research Group, University of Manchester, Clinical sciences Building, Salford Royal NHS Foundation Trust, Salford, UK.
  • Visscher PM; 1] Queensland Institute of Medical Research, Brisbane, Queensland, Australia [2] University of Queensland Diamantina Institute, University of Queensland, Princess Alexandra Hospital, Brisbane, Queensland, Australia [3] The Queensland Brain Institute, The University of Queensland, Brisbane, Queenslan
  • Deary IJ; 1] Department of Psychology, The University of Edinburgh, Edinburgh, UK [2] Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
Mol Psychiatry ; 19(1): 76-87, 2014 Jan.
Article en En | MEDLINE | ID: mdl-23207651
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Apolipoproteínas E / Envejecimiento / Cognición / Polimorfismo de Nucleótido Simple Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Apolipoproteínas E / Envejecimiento / Cognición / Polimorfismo de Nucleótido Simple Tipo de estudio: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Female / Humans / Male País/Región como asunto: Europa Idioma: En Revista: Mol Psychiatry Asunto de la revista: BIOLOGIA MOLECULAR / PSIQUIATRIA Año: 2014 Tipo del documento: Article País de afiliación: Reino Unido