High prevalence of vitamin D insufficiency in pregnant women working indoors and residing in Guiyang, China.
J Endocrinol Invest
; 36(7): 503-7, 2013.
Article
en En
| MEDLINE
| ID: mdl-23324526
ABSTRACT
BACKGROUND/AIM:
To assess the status of 25-hydroxyvitamin D [25(OH)D] in pregnant women in their second and third trimesters, who reside and work indoors in Guiyang, China. SUBJECTS ANDMETHODS:
A total of 311 pregnant women in their 12th to 40th gestational week were engaged in employment located indoors in the urban area of Guiyang and completed a questionnaire on living habits. Levels of serum 25(OH)D were measured from fasting venous blood by liquid chromatography-mass spectrometry (LC-MS/MS). Levels of 25(OH)D were classified as vitamin D deficient [25(OH)D<20 ng/ml], insufficient [20 ng/ml≤25(OH)D<30 ng/ml], or sufficient [25(OH)D≥30 ng/ml].RESULTS:
The mean serum level of 25(OH)D was 14.69±6.81 ng/ml. Vitamin D deficiency, insufficiency and sufficiency were found in 260 (83.6%), 39 (12.5%), and 12 (3.9%) women, respectively. The mean level of 25(OH)D in the third trimester was significantly higher than in the second trimester (p<0.001). The mean 25(OH)D level in summer (June, July, August) was significantly higher than in the other seasons (p<0.001). The 25(OH)D level in pregnant women compliant with pre-natal calcium or multivitamin supplements was higher than in those not taking supplements (p<0.001).CONCLUSIONS:
These results suggest that pregnant women residing in Guiyang urban area and working indoors are at high risk of vitamin D insufficiency, particularly during spring, winter, and autumn, regardless of use of pre-natal calcium and multivitamins. Appropriate vitamin D supplementation is necessary to improve maternal vitamin D nutrition.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Vitamina D
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Deficiencia de Vitamina D
Tipo de estudio:
Prevalence_studies
/
Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Pregnancy
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Endocrinol Invest
Año:
2013
Tipo del documento:
Article
País de afiliación:
China