PIUS: peptide identification by unbiased search.
Bioinformatics
; 29(15): 1913-4, 2013 Aug 01.
Article
en En
| MEDLINE
| ID: mdl-23709496
ABSTRACT
SUMMARY:
We present PIUS, a tool that identifies peptides from tandem mass spectrometry data by analyzing the six-frame translation of a complete genome. It differs from earlier studies that have performed such a genomic search in two ways (i) it considers a larger search space and (ii) it is designed for natural peptide identification rather than proteomics. Differently from other peptidomics tools designed for genome-wide searches, PIUS does not limit the analysis to a set of sequences that match a list of de novo reconstructions.AVAILABILITY:
Source code, executables and a detailed technical report are freely available at http//dtai.cs.kuleuven.be/ml/systems/pius. CONTACT eduardo.costa@cs.kuleuven.be SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Péptidos
/
Programas Informáticos
/
Espectrometría de Masas en Tándem
Tipo de estudio:
Diagnostic_studies
Límite:
Animals
Idioma:
En
Revista:
Bioinformatics
Asunto de la revista:
INFORMATICA MEDICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Bélgica