Collagenous sprue: don´t forget connective tissue in chronic diarrhea evaluation.
Rev Esp Enferm Dig
; 105(3): 171-4, 2013 Mar.
Article
en En
| MEDLINE
| ID: mdl-23735026
ABSTRACT
Collagenous sprue is a rare disease of the small bowel characterized by mucosal atrophy and excessive subepithelial collagen deposition. The etiology remains unclear and the diagnosis is based upon patient´s clinical picture and anatomopathological findings. Clinically, collagenous sprue is characterized by persistent diarrhoea, severe malabsorption, multiple nutrient deficiencies and progressive weight loss. Differential diagnosis includes celiac disease, which is mandatory to rule out because of their frequent association. Glutenfree diet is the first therapeutic step, but it usually is not effective. However, recent studies show high success rates with immunomodulators, mainly corticosteroids. We report the case of a patient presenting with chronic diarrhea and severe malabsorption who was diagnosed with collagenous sprue, with no response to gluten free diet, but with excellent response to budesonida.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Esprue Colágeno
Tipo de estudio:
Etiology_studies
Límite:
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
Rev Esp Enferm Dig
Asunto de la revista:
GASTROENTEROLOGIA
Año:
2013
Tipo del documento:
Article