A Txnrd1-dependent metabolic switch alters hepatic lipogenesis, glycogen storage, and detoxification.
Free Radic Biol Med
; 63: 369-80, 2013 Oct.
Article
en En
| MEDLINE
| ID: mdl-23743293
Palabras clave
5,5'-dithiobis(2-nitrobenzoic acid); ALT; APAP; ATP-binding cassette subfamily C multidrug-resistance transporters; Abcc; Aox1; BSO; Bioenergetics; CYP; Cre; DTNB; DTT; Drug metabolism; EDTA; GSH; GSSG; GST; Gsr; H&E; KEGG; Kyoto Encyclopedia of Genes and Genomes; MS; N-acetyl-p-benzoquinone imine; N-acetylcysteine; NAC; NADPH-quinine oxidase; NAPQI; Nqo1; ROS; Redox biology; SDS; SDS-PAGE; SDS-polyacrylamide gel electrophoresis; SEM; SULT; Sec; Thioredoxin reductase; Trx; TrxR; Txnip; UGDH; UGT; acetaminophen (paracetamol); alanine transaminase; aldehyde oxidase-1; bacteriophage P1 cyclization recombinase; buthionine sulfoximine; cytochrome P450; dithiothreitol; ethylenediamine tetraacetic acid; glutathione reductase; glutathione-S-transferase; hematoxylin and eosin; kDa; kilo-Dalton; loxP; mass spectrometry; oxidized glutathione disulfide; p-APDG; p-APDGS; p-acetamidophenyl-ß-D-glucronide; p-acetamidophenyl-ß-D-glucronide sodium salt; reactive oxygen species; recognition sites for Cre; reduced glutathione; selenocysteine; sodium dodecyl sulfate; standard error of the mean; sulfotransferase; thioredoxin mRNA or protein; thioredoxin reducatse-1 gene; thioredoxin reductase mRNA or protein; thioredoxin-interacting protein; txnrd1; uridine diphosphate-glucose dehydrogenase; uridine diphosphate-glucuronate transferase
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tiorredoxinas
/
Inactivación Metabólica
/
Tiorredoxina Reductasa 1
/
Glutatión
Límite:
Animals
Idioma:
En
Revista:
Free Radic Biol Med
Asunto de la revista:
BIOQUIMICA
/
MEDICINA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos