Functionalized viral nanoparticles as ultrasensitive reporters in lateral-flow assays.
Analyst
; 138(19): 5584-7, 2013 Oct 07.
Article
en En
| MEDLINE
| ID: mdl-23905160
ABSTRACT
Two types of viral nanoparticles were functionalized with target-specific antibodies and multiple copies of an enzymatic reporter (horseradish peroxidase). The particles were successfully integrated into an immunochromatographic assay detecting MS2 bacteriophage, a model for viral pathogens. The sensitivity of the assay was greatly superior to conventional gold nanoparticle lateral flow assays, and results could easily be evaluated, even without advanced lab instruments.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Levivirus
/
Virus de la Encefalitis Japonesa (Especie)
/
Nanopartículas
Límite:
Humans
Idioma:
En
Revista:
Analyst
Año:
2013
Tipo del documento:
Article
País de afiliación:
Estados Unidos