Immune-mediated myopathy related to anti 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies as an emerging cause of necrotizing myopathy induced by statins.

Lahaye, Clément; Beaufrére, Anne Marie; Boyer, Olivier; Drouot, Laurent; Soubrier, Martin; Tournadre, Anne

Immune-mediated myopathy related to anti 3-hydroxy-3-methylglutaryl-coenzyme A reductase antibodies as an emerging cause of necrotizing myopathy induced by statins.

Lahaye, Clément; Beaufrére, Anne Marie; Boyer, Olivier; Drouot, Laurent; Soubrier, Martin; Tournadre, Anne.

Afiliación

Lahaye C; CHU Clermont-Ferrand, Department of Rheumatology, Hôpital Gabriel-Montpied, 63003 Clermont-Ferrand, France.
Beaufrére AM; CHU Clermont-Ferrand, Department of Pathology, Hôpital Gabriel-Montpied, 63003 Clermont-Ferrand, France.
Boyer O; Inserm, U905, Normandie University, Rouen, France; Rouen University Hospital, Department of Immunology, Rouen, France.
Drouot L; Inserm, U905, Normandie University, Rouen, France.
Soubrier M; CHU Clermont-Ferrand, Department of Rheumatology, Hôpital Gabriel-Montpied, 63003 Clermont-Ferrand, France.
Tournadre A; CHU Clermont-Ferrand, Department of Rheumatology, Hôpital Gabriel-Montpied, 63003 Clermont-Ferrand, France. Electronic address: atournadre@chu-clermontferrand.fr.

Joint Bone Spine ; 81(1): 79-82, 2014 Jan.

Article en En | MEDLINE | ID: mdl-23953224

Asunto(s)

Acilcoenzima A/inmunología; Enfermedades Autoinmunes/inmunología; Inhibidores de Hidroximetilglutaril-CoA Reductasas/efectos adversos; Enfermedades Musculares/inmunología; Acilcoenzima A/antagonistas & inhibidores; Anciano; Autoanticuerpos; Enfermedades Autoinmunes/enzimología; Enfermedades Autoinmunes/patología; Enfermedades Autoinmunes/terapia; Biopsia; Humanos; Inmunoglobulinas Intravenosas/uso terapéutico; Masculino; Músculo Esquelético/patología; Enfermedades Musculares/enzimología; Enfermedades Musculares/patología; Enfermedades Musculares/terapia; Necrosis

Palabras clave

Anti-HMGCR; Myositis; Necrotizing myopathy; Statin

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Acilcoenzima A / Inhibidores de Hidroximetilglutaril-CoA Reductasas / Enfermedades Musculares Tipo de estudio: Prognostic_studies Límite: Aged / Humans / Male Idioma: En Revista: Joint Bone Spine Asunto de la revista: REUMATOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Francia

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