Dual-sugar imaging using isonitrile and azido-based click chemistries.
Org Biomol Chem
; 11(42): 7297-300, 2013 Nov 14.
Article
en En
| MEDLINE
| ID: mdl-24065211
ABSTRACT
We report the first account of metabolically labelling N-acetylglucosamine, in conjunction with either N-acetylgalactosamine or N-acetylmannosamine using a combination of isonitrile- and azide-based chemistries. With the appropriately labelled fluorescent probe molecules, that react with either the azido or isonitrile groups, the method enabled co-visualisation of cancer cell glycoproteins.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Acetilglucosamina
/
Azidas
/
Imagen Molecular
/
Química Clic
/
Colorantes Fluorescentes
/
Nitrilos
Idioma:
En
Revista:
Org Biomol Chem
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2013
Tipo del documento:
Article
País de afiliación:
Reino Unido