Uterine rupture in twin pregnancy with normal fetus and complete hydatidiform mole.
Gynecol Obstet Invest
; 77(2): 127-33, 2014.
Article
en En
| MEDLINE
| ID: mdl-24135120
ABSTRACT
We describe a rare case of complete hydatidiform mole with twin live fetus (CHMTF) confirmed by histopathology, flow cytometry and polymerase chain reaction techniques. No malformations were observed, fetal karyotype was normal and ß-human chorionic gonadotropin levels were high (>100,000 IU/ml). The patient was informed of the risks and decided to continue with the pregnancy, but at week 15, she had to undergo hysterectomy due to uterine rupture. She subsequently developed persistent trophoblastic disease (PTD) with pulmonary metastases that required treatment with polychemotherapy. Patients with CHMTF should be informed of all known risks, including the considerable risk of PTD, which is similar to or, even higher than that associated with a singleton complete mole. The risk does not appear to be increased by continuing the pregnancy. Because so few series have been published, there is a lack of evidence-based clinical management guidelines. To our knowledge, this is the first report of uterine rupture in CHMTF.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Uterinas
/
Rotura Uterina
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Mola Hidatiforme
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Enfermedad Trofoblástica Gestacional
/
Embarazo Gemelar
Tipo de estudio:
Guideline
Límite:
Adult
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Female
/
Humans
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Pregnancy
Idioma:
En
Revista:
Gynecol Obstet Invest
Año:
2014
Tipo del documento:
Article
País de afiliación:
España