Retest imaging of [11C]NOP-1A binding to nociceptin/orphanin FQ peptide (NOP) receptors in the brain of healthy humans.

Lohith, Talakad G; Zoghbi, Sami S; Morse, Cheryl L; Araneta, Maria D Ferraris; Barth, Vanessa N; Goebl, Nancy A; Tauscher, Johannes T; Pike, Victor W; Innis, Robert B; Fujita, Masahiro

Lohith, Talakad G; Zoghbi, Sami S; Morse, Cheryl L; Araneta, Maria D Ferraris; Barth, Vanessa N; Goebl, Nancy A; Tauscher, Johannes T; Pike, Victor W; Innis, Robert B; Fujita, Masahiro.

Afiliación

Lohith TG; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. Electronic address: lohithhere@gmail.com.
Zoghbi SS; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Morse CL; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Araneta MD; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Barth VN; Eli Lilly & Co., Indianapolis, IN, USA.
Goebl NA; Eli Lilly & Co., Indianapolis, IN, USA.
Tauscher JT; Eli Lilly & Co., Indianapolis, IN, USA.
Pike VW; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.
Innis RB; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA. Electronic address: robert.innis@nih.gov.
Fujita M; Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.

Neuroimage ; 87: 89-95, 2014 Feb 15.

Article en En | MEDLINE | ID: mdl-24225488

Asunto(s)

Encéfalo/diagnóstico por imagen; Péptidos Opioides/farmacocinética; Tomografía de Emisión de Positrones/métodos; Radiofármacos/farmacocinética; Receptores Opioides/análisis; Adulto; Área Bajo la Curva; Radioisótopos de Carbono/farmacocinética; Femenino; Humanos; Masculino; Receptores Opioides/metabolismo; Reproducibilidad de los Resultados; Adulto Joven; Receptor de Nociceptina; Nociceptina

Palabras clave

AUC; BSMSS; ICC; NOP; NOP receptors; Nociceptin; PET; Testretest imaging; V(T); WSMSS; area-under-the-curve; between-subject mean sum of squares; f(P); intraclass correlation coefficient; nociceptin/orphanin FQ peptide; plasma free fraction; positron emission tomography; retest variability; total distribution volume; within-subject mean sum of squares

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Receptores Opioides / Péptidos Opioides / Radiofármacos / Tomografía de Emisión de Positrones Tipo de estudio: Prognostic_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Neuroimage Asunto de la revista: DIAGNOSTICO POR IMAGEM Año: 2014 Tipo del documento: Article

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