Development of neural correlates of linear motion in the rat vestibular nucleus.
Sheng Li Xue Bao
; 66(1): 37-46, 2014 Feb 25.
Article
en En
| MEDLINE
| ID: mdl-24553868
ABSTRACT
The capability of the central vestibular system in utilizing cues arising from the inner ear determines the ability of animals to acquire the sense of head orientations in the three-dimensional space and to shape postural movements. During development, neurons in the vestibular nucleus (VN) show significant changes in their electrophysiological properties. An age-dependent enhancement of membrane excitability is accompanied by a progressive increase in firing rate and discharge regularity. The coding of horizontal and vertical linear motions also exhibits developmental refinement in VN neurons. Further, modification of cell surface receptors, such as glutamate receptors, of developing VN neurons are well-orchestrated in the course of maturation, thereby regulating synaptic efficacy and spatial coding capacity of these neurons in local circuits. Taken together, these characteristic features of VN neurons contribute to developmental establishment of space-centered coordinates within the brain.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Núcleos Vestibulares
/
Oído Interno
/
Movimiento
/
Neuronas
Límite:
Animals
Idioma:
En
Revista:
Sheng Li Xue Bao
Año:
2014
Tipo del documento:
Article
País de afiliación:
China