Sustained autoimmune mechanisms in dermatomyositis.
J Pathol
; 233(3): 215-6, 2014 Jul.
Article
en En
| MEDLINE
| ID: mdl-24687932
ABSTRACT
Dermatomyositis is an autoimmune disease predominantly affecting skin and muscle. Its poorly understood pathogenesis is increasingly being linked to the overproduction of type 1 interferon-inducible gene transcripts and proteins. Mechanisms have been identified by which chronic sustained accumulation of these proteins might occur and thereby injure tissue in dermatomyositis.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Transducción de Señal
/
Fibras Musculares Esqueléticas
/
Dermatomiositis
/
ARN Helicasas DEAD-box
/
Inmunidad Innata
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Pathol
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos