Macro-/micro-environment-sensitive chemosensing and biological imaging.
Chem Soc Rev
; 43(13): 4563-601, 2014 Jul 07.
Article
en En
| MEDLINE
| ID: mdl-24723011
ABSTRACT
Environment-related parameters, including viscosity, polarity, temperature, hypoxia, and pH, play pivotal roles in controlling the physical or chemical behaviors of local molecules. In particular, in a biological environment, such factors predominantly determine the biological properties of the local environment or reflect corresponding status alterations. Abnormal changes in these factors would cause cellular malfunction or become a hallmark of the occurrence of severe diseases. Therefore, in recent years, they have increasingly attracted research interest from the fields of chemistry and biological chemistry. With the emergence of fluorescence sensing and imaging technology, several fluorescent chemosensors have been designed to respond to such parameters and to further map their distributions and variations in vitro/in vivo. In this work, we have reviewed a number of various environment-responsive chemosensors related to fluorescent recognition of viscosity, polarity, temperature, hypoxia, and pH that have been reported thus far.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Espectrometría de Fluorescencia
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Chem Soc Rev
Año:
2014
Tipo del documento:
Article