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Optimization of anti-virulence PqsR antagonists regarding aqueous solubility and biological properties resulting in new insights in structure-activity relationships.
Lu, Cenbin; Kirsch, Benjamin; Maurer, Christine K; de Jong, Johannes C; Braunshausen, Andrea; Steinbach, Anke; Hartmann, Rolf W.
Afiliación
  • Lu C; Helmholtz-Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany.
  • Kirsch B; Helmholtz-Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany.
  • Maurer CK; Helmholtz-Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany.
  • de Jong JC; Helmholtz-Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany.
  • Braunshausen A; Helmholtz-Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany.
  • Steinbach A; Helmholtz-Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany.
  • Hartmann RW; Helmholtz-Institute for Pharmaceutical Research Saarland, Campus C2.3, 66123 Saarbrücken, Germany; Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C2.3, 66123 Saarbrücken, Germany. Electronic address: rolf.hartmann@helmholtz-hzi.de.
Eur J Med Chem ; 79: 173-83, 2014 May 22.
Article en En | MEDLINE | ID: mdl-24735643
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Quinolonas / Antibacterianos Idioma: En Revista: Eur J Med Chem Año: 2014 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
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PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pseudomonas aeruginosa / Quinolonas / Antibacterianos Idioma: En Revista: Eur J Med Chem Año: 2014 Tipo del documento: Article País de afiliación: Alemania