[Substance P: a peripheral inhibitor of gastric acid secretion in the rat]. / La substance P: un inhibiteur periphérique de la sécrétion gastrique acide chez le rat.

ABSTRACT

The inhibition of some peptidases in the central nervous system induces a decrease in gastric acid secretion. The present experiments indicate that substance P is not likely a candidate to mediate this effect in rats. Substance P, indeed, potently inhibits gastric acid secretion, but this effect appears mainly peripheral.