OncoSearch: cancer gene search engine with literature evidence.
Nucleic Acids Res
; 42(Web Server issue): W416-21, 2014 Jul.
Article
en En
| MEDLINE
| ID: mdl-24813447
ABSTRACT
In order to identify genes that are involved in oncogenesis and to understand how such genes affect cancers, abnormal gene expressions in cancers are actively studied. For an efficient access to the results of such studies that are reported in biomedical literature, the relevant information is accumulated via text-mining tools and made available through the Web. However, current Web tools are not yet tailored enough to allow queries that specify how a cancer changes along with the change in gene expression level, which is an important piece of information to understand an involved gene's role in cancer progression or regression. OncoSearch is a Web-based engine that searches Medline abstracts for sentences that mention gene expression changes in cancers, with queries that specify (i) whether a gene expression level is up-regulated or down-regulated, (ii) whether a certain type of cancer progresses or regresses along with such gene expression change and (iii) the expected role of the gene in the cancer. OncoSearch is available through http//oncosearch.biopathway.org.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Genes Relacionados con las Neoplasias
/
Motor de Búsqueda
Idioma:
En
Revista:
Nucleic Acids Res
Año:
2014
Tipo del documento:
Article