Antimicrobial Activity of Adenine-Based Inhibitors of NAD(+)-Dependent DNA Ligase.

Buurman, Ed T; Laganas, Valerie A; Liu, Ce Feng; Manchester, John I

Buurman, Ed T; Laganas, Valerie A; Liu, Ce Feng; Manchester, John I.

Afiliación

Buurman ET; Departments of Bioscience and Chemistry, AstraZeneca R&D Boston , Infection Innovative Medicines Unit, Waltham, Massachusetts 02451, United States.
Laganas VA; Departments of Bioscience and Chemistry, AstraZeneca R&D Boston , Infection Innovative Medicines Unit, Waltham, Massachusetts 02451, United States.
Liu CF; Departments of Bioscience and Chemistry, AstraZeneca R&D Boston , Infection Innovative Medicines Unit, Waltham, Massachusetts 02451, United States.
Manchester JI; Departments of Bioscience and Chemistry, AstraZeneca R&D Boston , Infection Innovative Medicines Unit, Waltham, Massachusetts 02451, United States.

ACS Med Chem Lett ; 3(8): 663-7, 2012 Aug 09.

Article en En | MEDLINE | ID: mdl-24900527

Palabras clave

LigA; antimicrobial; biochemical potency; efflux; mode of action; permeance

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Idioma: En Revista: ACS Med Chem Lett Año: 2012 Tipo del documento: Article País de afiliación: Estados Unidos

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