ATP signaling in skeletal muscle: from fiber plasticity to regulation of metabolism.
Exerc Sport Sci Rev
; 42(3): 110-6, 2014 Jul.
Article
en En
| MEDLINE
| ID: mdl-24949845
ABSTRACT
Tetanic electrical stimulation releases adenosine triphosphate (ATP) from muscle fibers through pannexin-1 channels in a frequency-dependent manner; extracellular ATP activates signals that ultimately regulate gene expression and is able to increase glucose transport through activation of P2Y receptors, phosphatidylinositol 3-kinase, Akt, and AS160. We hypothesize that this mechanism is an important link between exercise and the regulation of muscle fiber plasticity and metabolism.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ejercicio Físico
/
Adenosina Trifosfato
/
Fibras Musculares Esqueléticas
Límite:
Humans
Idioma:
En
Revista:
Exerc Sport Sci Rev
Año:
2014
Tipo del documento:
Article
País de afiliación:
Chile