Identification and functional characterization of novel nonsynonymous variants in the human multidrug and toxin extrusion 2-K.

Nishimura, Kenta; Ide, Ryosuke; Hirota, Takeshi; Kawazu, Kana; Kodama, Sho; Takesue, Hiroaki; Ieiri, Ichiro

Nishimura, Kenta; Ide, Ryosuke; Hirota, Takeshi; Kawazu, Kana; Kodama, Sho; Takesue, Hiroaki; Ieiri, Ichiro.

Afiliación

Nishimura K; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Ide R; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Hirota T; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Kawazu K; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Kodama S; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Takesue H; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
Ieiri I; Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan ieiri-ttr@umin.ac.jp.

Drug Metab Dispos ; 42(9): 1432-7, 2014 Sep.

Article en En | MEDLINE | ID: mdl-24985703

Asunto(s)

Proteínas de Transporte de Catión Orgánico/genética; Polimorfismo de Nucleótido Simple/genética; Alelos; Línea Celular; Membrana Celular/genética; Frecuencia de los Genes/genética; Genotipo; Células HEK293; Humanos; Cinética

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polimorfismo de Nucleótido Simple / Proteínas de Transporte de Catión Orgánico Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Drug Metab Dispos Asunto de la revista: FARMACOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Japón

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