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Immediate utility of two approved agents to target both the metabolic mevalonate pathway and its restorative feedback loop.
Pandyra, Aleksandra; Mullen, Peter J; Kalkat, Manpreet; Yu, Rosemary; Pong, Janice T; Li, Zhihua; Trudel, Suzanne; Lang, Karl S; Minden, Mark D; Schimmer, Aaron D; Penn, Linda Z.
Afiliación
  • Pandyra A; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Mullen PJ; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Kalkat M; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Yu R; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Pong JT; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Li Z; Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Trudel S; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Lang KS; Institute of Immunology, University Hospital, University of Duisburg-Essen, Essen, Germany.
  • Minden MD; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Schimmer AD; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Penn LZ; Princess Margaret Cancer Centre, Toronto, Ontario, Canada. Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. lpenn@uhnres.utoronto.ca.
Cancer Res ; 74(17): 4772-82, 2014 Sep 01.
Article en En | MEDLINE | ID: mdl-24994712
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Ácido Mevalónico Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cancer Res Año: 2014 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Ácido Mevalónico Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Cancer Res Año: 2014 Tipo del documento: Article País de afiliación: Canadá