The long-term effect of exercise on vascular risk factors and aerobic fitness in those with transient ischaemic attack: a randomized controlled trial.
J Hypertens
; 32(10): 2064-70, 2014 Oct.
Article
en En
| MEDLINE
| ID: mdl-25023152
ABSTRACT
OBJECTIVE:
Exercise has beneficial effects on vascular risk factors in transient ischaemic attack (TIA) patients within the sub-acute phase. This study examined whether TIA patients randomized to an early exercise and education programme within 2 weeks of TIA diagnosis would demonstrate improvements in cardiovascular risk factors and aerobic fitness 12 months post-diagnosis compared with control patients.METHODS:
A single-centre, randomized, parallel-group clinical trial. Sixty TIA patients (69â±â11 years) completed a vascular risk stratification baseline assessment and a physical fitness examination. Individuals were randomized to either an 8-week early exercise and education group or control group. Fifty-one patients attended post-intervention assessments that were completed immediately (post-intervention) and 12 months after (12PI).RESULTS:
A significantly greater improvement in resting SBP was observed between baseline and post-intervention for EX than for CON (-11âmmHg cf. -1âmmHg, respectively; Pâ<â0.05). The improvement in SBP was maintained between post-intervention and 12PI (Pâ>â0.05). Similar findings were demonstrated for BMI, bodyweight and peak oxygen uptake (Pâ<â0.05). Exercise blood pressure, pulse pressure and double product (SBPâxâheart rate; an indication of myocardial workload) were significantly lower at post-intervention and 12PI for EX than for CON (all Pâ<â0.05).CONCLUSION:
An 8-week exercise programme soon after TIA resulted in beneficial changes in resting and exercise blood pressure that were maintained for 12 months. CLINICAL TRIAL REGISTRATION http//www.anzctr.org.au/ TRIAL REGISTRATION NUMBER ACTRN12611000630910.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Ejercicio Físico
/
Ataque Isquémico Transitorio
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Aptitud Física
Tipo de estudio:
Clinical_trials
/
Etiology_studies
/
Risk_factors_studies
Límite:
Aged
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Hypertens
Año:
2014
Tipo del documento:
Article
País de afiliación:
Reino Unido