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Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.
Ramos, Yolande F M; Metrustry, Sarah; Arden, Nigel; Bay-Jensen, Anne C; Beekman, Marian; de Craen, Anton J M; Cupples, L Adrienne; Esko, Tõnu; Evangelou, Evangelos; Felson, David T; Hart, Deborah J; Ioannidis, John P A; Karsdal, Morten; Kloppenburg, Margreet; Lafeber, Floris; Metspalu, Andres; Panoutsopoulou, Kalliope; Slagboom, P Eline; Spector, Tim D; van Spil, Erwin W E; Uitterlinden, Andre G; Zhu, Yanyan; Valdes, Ana M; van Meurs, Joyce B J; Meulenbelt, Ingrid.
Afiliación
  • Ramos YF; Department of Molecular Epidemiology, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands.
  • Metrustry S; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • Arden N; NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, UK Arthritis Research UK, Sport, Exercise and Osteoarthritis Centre of Excellence, London, UK.
  • Bay-Jensen AC; Department of Rheumatology, Nordic Bioscience, Herlev, Denmark.
  • Beekman M; Department of Molecular Epidemiology, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands.
  • de Craen AJ; Department of Gerontology and Geriatrics, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands.
  • Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA The Framingham Heart Study, Framingham, Massachusetts, USA.
  • Esko T; Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia Department of Endocrinology, Children's Hospital Boston, Boston, Massachusetts, USA Broad Institute, Cambridge, Massachusetts, USA.
  • Evangelou E; Department of Hygiene & Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • Felson DT; Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts, USA.
  • Hart DJ; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • Ioannidis JP; Department of Hygiene & Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece Department of Medicine, Stanford Prevention Research Center, Stanford, USA Department of Health Research and Policy, Stanford University School of Medicine, Stanford, USA Department of Statistics, S
  • Karsdal M; Department of Rheumatology, Nordic Bioscience, Herlev, Denmark.
  • Kloppenburg M; Department of Rheumatology & Clinical Epidemiology, LUMC, Leiden, The Netherlands.
  • Lafeber F; Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht, The Netherlands.
  • Metspalu A; Institute of Molecular and Cell Biology and Estonian Genome Center, University of Tartu, Tartu, Estonia.
  • Panoutsopoulou K; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
  • Slagboom PE; Department of Molecular Epidemiology, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands.
  • Spector TD; Department of Twin Research & Genetic Epidemiology, King's College London, London, UK.
  • van Spil EW; Department of Rheumatology & Clinical Immunology, UMC Utrecht, Utrecht, The Netherlands.
  • Uitterlinden AG; The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Zhu Y; Global Analytical Science, Takeda Pharmaceuticals International Co., Cambridge, Massachusetts, USA.
  • Valdes AM; Academic Rheumatology, University of Nottingham, Nottingham, UK.
  • van Meurs JB; The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Meulenbelt I; Department of Molecular Epidemiology, LUMC, Leiden, The Netherlands The Netherlands Genomics Initiative-Sponsored Netherlands Consortium for Healthy Aging, Leiden and Rotterdam, The Netherlands.
J Med Genet ; 51(9): 596-604, 2014 Sep.
Article en En | MEDLINE | ID: mdl-25057126
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Fragmentos de Péptidos / Variación Genética / Receptores Inmunológicos / Biomarcadores / Colágeno Tipo II / Proteína de la Matriz Oligomérica del Cartílago / Proteínas de la Membrana Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: J Med Genet Año: 2014 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteoartritis / Fragmentos de Péptidos / Variación Genética / Receptores Inmunológicos / Biomarcadores / Colágeno Tipo II / Proteína de la Matriz Oligomérica del Cartílago / Proteínas de la Membrana Tipo de estudio: Systematic_reviews Límite: Humans Idioma: En Revista: J Med Genet Año: 2014 Tipo del documento: Article País de afiliación: Países Bajos