microManaging mitochondrial translation.
Cell
; 158(3): 477-8, 2014 Jul 31.
Article
en En
| MEDLINE
| ID: mdl-25083863
Regulation of gene expression in mammalian mitochondria by microRNAs is reported by Zhang et al. During muscle cell differentiation, localization of a miRNA is increased within mitochondria, where it interacts with Ago2 to selectively activate translation of mtDNA-encoded mRNAs. The findings represent a new mitochondrial regulatory pathway and a potentially powerful means to purposefully manipulate mtDNA expression.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Biosíntesis de Proteínas
/
Diferenciación Celular
/
Miocitos Cardíacos
/
Mioblastos
/
MicroARNs
/
Mitocondrias
Límite:
Animals
Idioma:
En
Revista:
Cell
Año:
2014
Tipo del documento:
Article
País de afiliación:
Estados Unidos