Penehyclidine hydrochloride decreases pulmonary microvascular permeability by upregulating beta arrestins in a murine cecal ligation and puncture model.

Zhan, Jia; Xiao, Fei; Li, Jin-Jie; Zhang, Zong-Ze; Chen, Kai; Wang, Yi-Peng; Wang, Yan-Lin

Zhan, Jia; Xiao, Fei; Li, Jin-Jie; Zhang, Zong-Ze; Chen, Kai; Wang, Yi-Peng; Wang, Yan-Lin.

Afiliación

Zhan J; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Xiao F; Department of Osteology, Pu Ai Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China.
Li JJ; Department of Anesthesiology, Hospital of Stomatology, Wuhan University, Wuhan, Hubei, People's Republic of China.
Zhang ZZ; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Chen K; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Wang YP; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China.
Wang YL; Department of Anesthesiology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, People's Republic of China. Electronic address: jia19811001@163.com.

J Surg Res ; 193(1): 391-8, 2015 Jan.

Article en En | MEDLINE | ID: mdl-25096356

Asunto(s)

Lesión Pulmonar Aguda/tratamiento farmacológico; Arrestinas/metabolismo; Antagonistas Colinérgicos/farmacología; Pulmón/irrigación sanguínea; Quinuclidinas/farmacología; Lesión Pulmonar Aguda/metabolismo; Animales; Permeabilidad Capilar/efectos de los fármacos; Ciego/lesiones; Antagonistas Colinérgicos/química; Modelos Animales de Enfermedad; Femenino; Ligadura; Pulmón/metabolismo; Ratones Endogámicos; Microcirculación/efectos de los fármacos; FN-kappa B/metabolismo; Circulación Pulmonar/efectos de los fármacos; Quinuclidinas/química; Distribución Aleatoria; Regulación hacia Arriba/efectos de los fármacos; Heridas Punzantes; beta-Arrestinas

Palabras clave

Beta arrestins; Cecal ligation and puncture; Penehyclidine hydrochloride; Pulmonary microvascular permeability

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinuclidinas / Antagonistas Colinérgicos / Arrestinas / Lesión Pulmonar Aguda / Pulmón Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Surg Res Año: 2015 Tipo del documento: Article

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