A modular approach for the synthesis of nanometer-sized polynitroxide multi-spin systems.
J Org Chem
; 79(17): 8313-23, 2014 Sep 05.
Article
en En
| MEDLINE
| ID: mdl-25102422
ABSTRACT
The synthesis of rigid symmetric polyradical model systems with inter-spin distances between 1.4 and 4 nm and their room temperature continuous wave (CW) EPR spectra are reported. Conditions for attachment of the spin-label via esterification have been optimized on the direct synthesis of polyradicals from commercially available polyphenols and the carboxylic acid functionalized nitroxide TPC. A common synthetic protocol utilizing 4-hydroxy-4'-iodobiphenyl as a key building block has been used to synthesize an equilateral biradical and a triradical in only two steps from commercially available starting materials. The first synthesis of a tetraradical based upon an adamantane core bearing six equivalent nitroxide-nitroxide distances is also reported. These systems are very promising candidates for studying multi-spin effects in pulsed EPR distance measurements.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polifenoles
/
Óxidos de Nitrógeno
Idioma:
En
Revista:
J Org Chem
Año:
2014
Tipo del documento:
Article
País de afiliación:
Reino Unido