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Novel N-biphenyl-2-ylmethyl 2-methoxyphenylpiperazinylalkanamides as 5-HT7R antagonists for the treatment of depression.
Kim, Youngjae; Tae, Jinsung; Lee, Kangho; Rhim, Hyewhon; Choo, Il Han; Cho, Heeyeong; Park, Woo-Kyu; Keum, Gyochang; Choo, Hyunah.
Afiliación
  • Kim Y; Center for Neuro-Medicine, Korea Institute of Science and Technology, Seongbuk-gu, Seoul 136-791, Republic of Korea; Department of Chemistry, Yonsei University, Seodaemun-gu, Seoul 120-749, Republic of Korea.
  • Tae J; Department of Chemistry, Yonsei University, Seodaemun-gu, Seoul 120-749, Republic of Korea.
  • Lee K; Center for Neuroscience, Korea Institute of Science and Technology, Seongbuk-gu, Seoul 136-791, Republic of Korea; Department of Neuroscience, University of Science and Technology, Yuseong-gu, Daejeon 305-350, Republic of Korea.
  • Rhim H; Center for Neuroscience, Korea Institute of Science and Technology, Seongbuk-gu, Seoul 136-791, Republic of Korea; Department of Neuroscience, University of Science and Technology, Yuseong-gu, Daejeon 305-350, Republic of Korea.
  • Choo IH; School of Medicine, Chosun University, Dong-gu, Kwangju 501-759, Republic of Korea.
  • Cho H; Pharmacology Research Center, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 305-343, Republic of Korea.
  • Park WK; Pharmacology Research Center, Korea Research Institute of Chemical Technology, Yuseong-gu, Daejeon 305-343, Republic of Korea.
  • Keum G; Center for Neuro-Medicine, Korea Institute of Science and Technology, Seongbuk-gu, Seoul 136-791, Republic of Korea; Department of Biological Chemistry, University of Science and Technology, Yuseong-gu, Daejeon 305-350, Republic of Korea. Electronic address: gkeum@kist.re.kr.
  • Choo H; Center for Neuro-Medicine, Korea Institute of Science and Technology, Seongbuk-gu, Seoul 136-791, Republic of Korea; Department of Biological Chemistry, University of Science and Technology, Yuseong-gu, Daejeon 305-350, Republic of Korea. Electronic address: hchoo@kist.re.kr.
Bioorg Med Chem ; 22(17): 4587-96, 2014 Sep 01.
Article en En | MEDLINE | ID: mdl-25127461
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Receptores de Serotonina / Depresión / Amidas / Antidepresivos Límite: Animals / Humans / Male Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Piperazinas / Receptores de Serotonina / Depresión / Amidas / Antidepresivos Límite: Animals / Humans / Male Idioma: En Revista: Bioorg Med Chem Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2014 Tipo del documento: Article