MicroRNA-539 is up-regulated in failing heart, and suppresses O-GlcNAcase expression.

Muthusamy, Senthilkumar; DeMartino, Angelica M; Watson, Lewis J; Brittian, Kenneth R; Zafir, Ayesha; Dassanayaka, Sujith; Hong, Kyung U; Jones, Steven P

Muthusamy, Senthilkumar; DeMartino, Angelica M; Watson, Lewis J; Brittian, Kenneth R; Zafir, Ayesha; Dassanayaka, Sujith; Hong, Kyung U; Jones, Steven P.

Afiliación

Muthusamy S; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202.
DeMartino AM; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202.
Watson LJ; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202.
Brittian KR; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202.
Zafir A; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202.
Dassanayaka S; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202.
Hong KU; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202.
Jones SP; From the Institute of Molecular Cardiology, and, Diabetes and Obesity Center, University of Louisville, Louisville, Kentucky 40202 Steven.P.Jones@Louisville.edu.

J Biol Chem ; 289(43): 29665-76, 2014 Oct 24.

Article en En | MEDLINE | ID: mdl-25183011

Asunto(s)

Insuficiencia Cardíaca/genética; MicroARNs/metabolismo; Regulación hacia Arriba/genética; beta-N-Acetilhexosaminidasas/metabolismo; Regiones no Traducidas 3'/genética; Animales; Secuencia de Bases; Hipoxia de la Célula/genética; Regulación hacia Abajo/genética; Glicosilación; Células HEK293; Pruebas de Función Cardíaca; Humanos; Ratones Endogámicos C57BL; MicroARNs/genética; Datos de Secuencia Molecular; Infarto del Miocardio/genética; Infarto del Miocardio/fisiopatología; Miocardio/metabolismo; Miocardio/patología; Miocitos Cardíacos/metabolismo; Oxígeno/metabolismo; Ratas Sprague-Dawley

Palabras clave

Heart Failure; Hexosamine; Metabolism; MicroRNA (miRNA); O-GlcNAcylation; Post-transcriptional Regulation

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Beta-N-Acetilhexosaminidasas / Regulación hacia Arriba / MicroARNs / Insuficiencia Cardíaca Límite: Animals / Humans Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

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